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Saving the Animals: New Ways to Test Products - The New York Times Saving the Animals: New Ways to Test Products - The New York Times
12 Sep 2007 ... TEST TUBE SKIN At L'Oréal Research, products are tested on reconstructed ... and director of the Center for Alternatives to Animal Testing at Johns .... said that its tissue testing products and services were sold at cost to other ...

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But in many ways the alternatives are driven by a few giants eager to move from animal testing for scientific, business and image reasons. Fda issues numerous alerts warning consumers and health care professionals about potentially dangerous products. Many of these products are produced overseas in facilities that have not yet been inspected by fda.

Admet owns in vitro laboratories, which charges up to 20,000 to screen a drug against liver cells and other human tissues for toxic effects. Human skin, eyes, the lining of the throat snippets of these and other tissues are now routinely grown in test tubes from donated human cells. People with diabetes, high blood pressure, high cholesterol or heart disease are often prescribed drugs containing nitrates, and men with those conditions commonly suffer from erectile dysfunction.

The methods for engineering tissue samples are among the most complex of an expanding portfolio of technologies intended to eliminate or reduce animal testing. The goal is not to patch up ailing people but to use the human tissues in place of mice, dogs or other lab animals for testing new drugs, cosmetics and other products. We dont know what danger this poses because these combinations have never been studied before theyre sold to unsuspecting consumers, coody says.

Goldberg, a toxicology professor and director of the center for alternatives to animal testing at johns hopkins university, a nonprofit research group founded in 1981. Under the law, it is the companys responsibility to make sure that its products are safe and that the claims they make are true. The high costs and concerns about reliability, however, have been the biggest forces behind the shift away from tests on animals.

For companies, animal testing can be a public relations nightmare, involving confrontations with animal-rights activists, or less intense but still negative reactions from consumers. Industry executives say that as much as 25 percent of the drugs tested on animals failed to show side effects that later proved serious enough to prevent the drugs from being marketed. Consumers may be misled to believe these products are safe because their labeling often suggests they are all-natural or herbal alternatives to fda-approved prescription drugs for the treatment of ed.

The big risk for unsuspecting men is that many of the unlabeled drug ingredients in these deceptive products can interact dangerously with other drugs they are taking, such as heart disease medicines. Patricia pineau, loréal researchs spokeswoman, who said that its tissue testing products and services were sold at cost to other companies, including rivals like p. In other cases, testing is being conducted virtually, using computers and simulation software. The governments statistics are limited to cats, dogs, primates and a few other species and do not cover birds or fish, or the most common lab animals, mice and rats. Such software incorporates hundreds of variables to simulate how humans who suffer from conditions like asthma, obesity or type 1 or 2 diabetes will react to a new drug.


FAQs - Resources - Altweb: Alternatives to Animal Testing - Johns ...


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Product Testing On Animals Alternatives To Viagra Sale Failure to cease illegal behavior could lead to seizures, import alerts, injunctions, The tissues take up to four weeks to grow in the test kits in which they are shipped, said john sheasgreen, the companys president. Concern about the costs and questionable benefits of animal testing has been growing since the 1970s, Even a cautious consumer cant tell that these products are, in fact, tainted with undisclosed drug ingredients. That might pose novel hazards, and some reported tests of carbon nanoparticles, called fullerenes, had shown alarmingly that they killed various human cell samples in test tubes. Analysts estimate that businesses spent 716 million last year for contract research at labs that specialize in such alternative techniques. If consumers are taking products that have undeclared drug ingredients, An import alert allows fda to detain, without physically examining. Men, Immediately generic to the cadaver it is research with night, canadian generic. A: Most products manufactured for human use must be tested for safety before they can be sold to . If you suspect that a product marketed as a dietary supplement may be tainted,.
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    Concern about the costs and questionable benefits of animal testing has been growing since the 1970s, and the number of lab animals sacrificed in the united states has fallen since then by nearly 50 percent among the species tracked by the department of agriculture the total was 1. Stephens said, european regulators and industries have a 10-year lead in adopting alternatives in the united states, where there have been no similar government mandates to reduce animal testing. And loréal, the french cosmetics giant, says it has spent more than 800 million over the same period. Charles river laboratories, the worlds largest supplier of genetically engineered rodents for labs, also has a subsidiary called endosafe, which provides an alternative to the testing of solutions in rabbits eyes for contamination with fever-producing bacteria. These can include the same active ingredients found in prescription drugs that are fda-approved for the treatment of erectile dysfunction (ed), such as viagra, cialis and levitra.

    Men, beware! Products falsely marketed as dietary supplements or foods that promise to enhance your sexual performance or increase sexual stimulation might contain hidden drug ingredients or other undisclosed ingredients and can endanger your health. A technician in lyon, france, holds up a flask in which human skin cells are growing. And for some tests, people have replaced animals volunteers get microdoses of potential drugs that can be analyzed but cause no ill effects. In many cases, we dont know where or how these products are manufactured, says brad pace, regulatory counsel at fdas health fraud branch. That includes deals to buy episkin and skinethic, two companies that make alternative tests.

    Another push has come from european legislation, which requires companies to provide safety data for about 30,000 chemicals over the next 11 years. Warheit said, he believes the live-rat studies produced a more accurate reading on the risks than the test-tube experiments did. Curren, president of the institute for in-vitro sciences, a nonprofit testing center in gaithersburg, md. The tissues take up to four weeks to grow in the test kits in which they are shipped, said john sheasgreen, the companys president. Such software incorporates hundreds of variables to simulate how humans who suffer from conditions like asthma, obesity or type 1 or 2 diabetes will react to a new drug. The study concluded that over time, the use of animals for testing could be greatly reduced and possibly eliminated. Fda-approved for the treatment of ed, such as cialis and viagra, promising to work quickly within 30 to 40 minutes. Patricia pineau, loréal researchs spokeswoman, who said that its tissue testing products and services were sold at cost to other companies, including rivals like p. Warheit, who oversees research at dupont on the potential hazards of new nanoscale materials, cited his own experience as an example. Failure to cease illegal behavior could lead to seizures, import alerts, injunctions, recalls and criminal prosecutions.

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